Mounjaro week by week

Mounjaro, milestone by milestone

1. Days 1-7

   First injection at 2.5 mg. Sub-therapeutic for A1C control. Some appetite reduction.

2. Weeks 4-12

   Titration through 5 → 7.5 mg. A1C-lowering effect begins. Weight loss starts (4-8 lbs typical by week 12).

3. Months 3-6

   Most patients reach 10 mg. A1C drops 2-2.3 percentage points. Weight loss 8-12%.

4. Months 6-12

   Maintenance at 10 or 15 mg. SURPASS-2 cohort averaged 2.3% A1C reduction and ~12% weight loss at 40 weeks.

5. Month 12+

   Maximum effects sustained. Re-evaluation by endo typical.